Learning Centre

Imaging and Spectroscopy Tools to Understand Material Self-Healing Mechanisms — Technical Article
In the world of material science – how does one extend a material’s functional lifetime? The field of self-healing materials is pursuing one solution to this question as scientists and en…
RISE Microscopy for Biomineralization Studies — Webinars
Over the years biominerals have been refined by natural selection, leading to the unique forms and functions we observe today. These forms can be studied at high resolution usin…
TSV Plasma Polish Optimization and AFM characterization for Quantum Computing — Webinars
Check out our on-demand webinar showcasing how the Oxford Instruments Jupiter AFM was used to characterize sidewall roughness in through-silicon vias (TSVs)—a critical fac…
Investigating the Dynamics of Neural Injury Using the Dragonfly with the MicroPoint Ablation Laser — Application Notes
In the Kucenas Lab, we are fascinated by the cellular and molecular mechanisms that drive glial development. Using zebrafish (Danio rerio), coupled with genetic and pharmacological perturbation, sing…
Andor Solutions for Situational Awareness — Solution Note
Surveillance systems are critical to the operation of modern security services, providing situational awareness that supports strategic planning and tactical decision making alongside accurate detect…
Torsional Force Microscopy of Twisted 2D Materials — Application Video
Determining the twist angle of stacked 2D materials by imaging the moiré periodicity is a critical step in the fabrication and characterization of these materials. But so…
Advanced and Customizable Camera Technology for Direct Detection of X-rays — Application Notes
Development of soft X-ray (20 eV to 10 keV) sources has led to an increasingly wide application of X-ray spectroscopy, microscopy, and tomography for studying material and biological systems. As expe…
BC43 - Compact & Upgradeable Benchtop Fluorescence Microscope for Multi-scale Imaging Cell Biology — Webinars
With the latest expansion of our Benchtop Microscope range, adding application and budget-based flexibility to the original BC43 Benchtop Confocal. We can now offer more choice …
The Dragonfly Series: Revolutionising Life Science Imaging — Webinars
There is a growing need to use novel technologies and experimental methodologies that can push the boundaries of research. Confocal microscopy has become an essential tool and a…
A New Generation of InGaAs based Cameras for NIR II Imaging of Thicker, More Biologically Relevant Tissues — Technical Article
Fluorescence microscopy, aided most notably by the development of labels such as GFP and its variants, have enabled significant advancements in our understanding of the many processes within cells, a…
Creating Impactful Scientific Animations with Imaris 10.2: Advanced Techniques for Biological Research — Webinars
In biological research, effective visualisation is crucial for communicating complex scientific findings. This webinar, tailored for researchers across all biological discipline…
Andor Virtual Camera – A Versatile Tool for Photostimulation Targeting — Technical Article
Photostimulation techniques (PS) are important tools for the study of materials and live biological specimens. Typically, PS uses targeted optical radiation to induce some kind of change (temporary o…
BC43 - Compact & Upgradeable Benchtop Fluorescence Microscope for Multi-scale Imaging in Neuroscience Research — Webinars
With the latest expansion of our Benchtop Microscope range, adding application and budget-based flexibility to the original BC43 Benchtop Confocal. We can now offer more choice …
An Introduction to Nonlinear Spectroscopies for Interfacial Studies — Webinars
Surface-specific nonlinear spectroscopies, such as second-harmonic and sum-frequency generation (SHG and SFG), are powerful optical tools that can probe the chemical and physica…
Using Near Infra-red Dyes to Deal with Autofluorescence Background in Biological Samples — Application Notes
When the aim of an experiment is to image single molecules, autofluorescence background can impede their detection. In cells, a major contribution to the fluorescence background is from autofluoresce…
Solutions for Helium Supply Challenges for Optical Cryostats — Solution Note
Helium is one of the most abundant elements in the universe, however here on Earth it is considered a non-renewable resource. Once released into the atmosphere it is rises until eventually escaping i…
High Speed and Resolution LIBS Spectroscopy with sCMOS Cameras — Solution Note
LIBS Spectroscopy and its Applications Over the past two decades, Laser-Induced Breakdown Spectroscopy (LIBS) has rapidly emerged as a ubiquitous technique for the elemental characterization of mate…
Exploring Modern Fluorescence Microscopy — Webinars
During this webinar, Dr Claudia Florindo will present the concept of fluorescence, and how this physical property is applied to microscopy. We will also give a brief overview of…
C-RED 2 Lite - Temperature Stabilized SWIR Imaging — Application Notes
C-RED 2 Lite is a 640 x 512 stabilized SWIR camera running at 600 FPS full frame. The camera design optimizes temperature management and enables precise sensor stabilization despite environmental flu…
Raman Spectroscopic Analysis of the β-Carotene Content of Chicken Skins — Application Notes
Raman spectroscopy is widely used in medical and life science research. As an important tool for learning about biological macromolecules, molecular-level information can be obtained by analyzing cha…
iStar sCMOS Demo Exercises: External Triggering: Impedance, Grounding, and Jitter — Tutorials
Abstract The ns time scale measurement capability of the iStar intensified cameras allows for increasingly complex and novel measurements synchronized with a lab full of other …
iStar sCMOS Demo Exercises: External Triggering And Troubleshooting — Tutorials
Abstract The ns time scale measurement capability of the iStar intensified cameras allows for increasingly complex and novel measurements synchronized with a lab full of other …
Session 2: Spectroscopy Techniques in Practice - Methods and Motivations — Webinars
  During this session we’ll break down some common spectroscopic techniques – UV/VIS absorption spectroscopy, photoluminescence, and Raman scattering among o…
Session 1: The Basic Physics of Spectroscopy - Light-Matter Interaction for Fun and Profit — Webinars
In this session, we’ll cover concepts fundamental to understanding common optical spectroscopy methods. Specifically, we’ll talk about how light - an electromagnetic…
X-Ray Tomography of Soft Tissue at the Synchrotron Endstation — Application Notes
Propagation-based Phase-contrast X-ray Tomography of Soft Tissue with Zyla-HF sCMOS Camera at the Synchrotron Endstation The interaction of electromagnetic waves with matter is described by the inde…
Imaging of Intracellular Signalling in Cardiovascular Cells — Solution Note
Challenge Background Calcium imaging is a widely used technique which can be used to study cell signalling in cell types such as neurons and cardiomyocytes. Fluorescent indicators such as fura-2, fl…
High Speed SWIR Hyperspectral Imaging with C-RED 3 — Application Notes
Hyperspectral imaging combines conventional spectroscopy and imaging to simultaneously gather spectral and spatial information. The sensitivity and speed of the C-RED 3 camera are key assets to optim…
Using Confocal Spinning Disk Microscopy to Understand the Molecular Basis of Hearing Disorders — Application Notes
Using Dragonfly to Visualise Hair Cell Dynamics One in five adults in the UK is deaf or has some degree of hearing loss. Hearing impairment results in communication difficulties and can lead to an i…
PICASSO and Wholebody-Expansion Microscopy for Ultra-Multiplexed Imaging and Wholebody Super-Resolution Imaging — Webinars
  AbstractFluorescence microscopy imaging has been widely used in neuroscience and cancer research, but it  still has two limitations: (1) the number of fluorophores that can b…
Imaris 9.8 Launch Webinar - I Can See Clearly Now — Webinars
Imaris 9.8 brings several usability improvements for its users, including easier volume visualisation modes and virtual sample sectioning (clipping planes), which are particular…
Scalable Tests of Fundamental Physics with Multiple Trapped Ytterbium Ions — Application Notes
Precision laser spectroscopy of trapped ions has proven to be a precise tool not only to build high-precision optical clocks but also to find applications in quantum computing [1,2]. In addition, the…
Microscopy School Lesson 2 – Transmitted Light Microscopy — Webinars
Although recent advances have offered researchers many sophisticated imaging technologies, transmitted light microscopy techniques are still applicable to a wide variety of rese…
Microscopy School Lesson 1 – The History of Microscopy — Webinars
Microscopes are very complex pieces of equipment that most often required in-depth knowledge and expertise to be able to take full advantage of its potential. Current microscopy…
Balor Very Large Area sCMOS Camera for Astronomy — Webinars
In this webinar, Product Manager Dr Colin Coates introduces Balor, Andor’s innovative Very Large Area sCMOS Camera for Astronomy. Combining a very large 16.9 Megapixel, 70m…
In Vivo Bioluminescence based Studies of the Circadian Clock in Arabidopsis — Case Studies
Research Group All organisms from basic single-cell organisms through to complex multicellular organisms, including humans, are subject to a 24-hour cycle due to the rotation of the earth. Organisms…
Seeing through the Murine Heart - Quantitative 3D Assessment of Myocardial Ischemia/Reperfusion Injury and Response — Webinars
During this webinar, speakers present a three-dimensional (3D), simultaneous quantitative investigation of key ischemia/reperfusion injury-components by combining bleaching-augmen…
How to Overcome the Challenges in Analysing Vesicle Trafficking — Solution Note
Challenge Background Extracellular or intracellular vesicles perform vital functions in inter/intracellular communication. Not surprisingly, the de-regulation of the endocytic pathway affects numero…
Calculating the Signal to Noise Ratio of a Camera — Technical Article
An important parameter that is often used to evaluate the sensitivity of a camera is the signal to noise ratio. This can be used to determine how different cameras may perform at light regimes that s…
Overview of Bio/Chemi-Luminescence in Life Sciences — Application Notes
Bioluminescence refers to the ability of living things to produce light and represents a fascinating and profoundly useful area of biophotonic research. Not only is it of interest to study and record…
Sub-Bandgap Photoluminescence Study on Implantation-Induced Color Centers in 4H-SiC — Application Notes
Fig. 1: Optical setup Defect centers in silicon carbide (SiC) capable of visible and near-infrared luminescence (color centers) have attracted great attention in recent years due to their potential …
Probing Molecular Structure with Low Frequency Raman Spectroscopy — Application Notes
Watch The Webinar Webinar: Raman Spectroscopy - A New Dawn In Clinical Diagnosis Raman spectroscopy has become an extremely valuable tool for measuring and identifying chemical composition and mole…
Unlocking The Mysteries Of The Formation Of Our Solar System With CHIMERA — Webinars
Professor Gregg Hallinan (Caltech) discusses the development of the Caltech High-Speed Multi-Color Camera (CHIMERA) which has been used to analyse, for the first time ever, occultations occuring in t…
Biofilms In Imaris Tutorial — Tutorials
This tutorial describes how Imaris can be used for quantifying three-dimensional biofilm images. Imaris features will be shown using the confocal 3D human pathogen Vibrio cholerae image…
Biofilm Formation — Webinars
Spectral characteristics of an integrated Type-I parametric down-conversion source — Application Notes
In recent research on quantum communication parametric down-conversion (PDC) in χ(2)-nonlinear crystals play a major role for the generation of photon pairs (see e.g. [1], [2], [3]). In particula…
Using Similarity Statistic Values — Tutorials
In large data sets, in which each object has multiple statistical attributes, identifying groups of objects that are similar to each other in some aspects but different from others within the same im…
An Introduction to the Basic Principles of LIBS (Laser-Induced-breakdown-Spectroscopy) — Webinars
ImarisXT Introduction — Webinars
Ay, There's the Rub: An AFM Investigation of Tribofilm Formation — Application Notes
Areas of sliding contact between load-bearing surfaces such as gears, bearings, and pistons are the most likely sites of failure in mechanical systems [i]. These interfaces are typically under high m…
How to Analyse your Data Using Interactive Vantage Plots in Imaris — Webinars
In this webinar session Imaris Sales Manager, Dr. Daniel Reisen will demonstrate how to analyse data using interactive Vantage plots in Imaris. Dr. Daniel Reisen holds a PhD in …
How to get Statistics from your Objects when you have Multiple Reference Frames — Tutorials
In this tutorial video you will learn how to report statistics in 2 coordinate systems (reference frames) and export your tratistics to .xls or .csv.
How to add and Manually Position a Reference Frame — Tutorials
In this short video tutorial, you will learn how to add Reference Frame to your microscopy dataset and place it in the center of an object to get positions in a new XYZ coordinate…
Identifying LISA Gravitational-Wave Sources Using the Optical Time Domain — Webinars
In this webinar, Kevin Burdge (Graduate Student, Caltech) will describe ongoing work using the Zwicky Transient Facility (ZTF) to identify ultracompact binaries (P below 60 min)…
What is Expansion Microscopy? — Technical Article
How can you get the Most Information from Expanded Samples? Traditional light microscopy is limited by the diffraction of light. Consequently, features less than 200 nm apart cannot be resolved. For…
Resolving Subcellular Structure in Large Volumes of the Songbird Brain — Case Studies
Daniel Düring and colleagues from University of Zürich/ETH Zürich in Switzerland and Max Planck Institute for Ornithology in Germany are combining expansion microscopy with conventiona…
New Approaches Help Tease out Molecular Architecture of Multiprotein Complex — Case Studies
Markus Sauer and colleagues at the University of Würzburg in Germany are combining a sample preparation approach called expansion microscopy with structured illumination microscopy to make new d…
Importing Data into Imaris — Tutorials
The very first step to open a file in Imaris is to convert it into IMS format. To do so, we can either use Arena directly, or, if you want to convert files in batch, we can use th…
Intensity versus Object Based Coloc — Tutorials
Many biological studies involve the interaction of various objects within the biological system. In Imaris, we provide both intensity based and object based colocalization for stu…
Import Surfaces and Spots to Cell — Tutorials
Imaris Cell module provides compartmentalized quantitative information that can be useful in many applications. However, the automatic Cell detection may not work for more challen…
Testing an Andor Marana sCMOS Camera for High Speed Astronomical Image Acquisition — Case Studies
“We were able to capture conventional images with high contrast and fine detail in only a fraction of the exposure time needed with conventional cameras. Even shorter exposures would be possibl…
Laser-Induced Breakdown Spectroscopy (LIBS) for in-situ Fuel Retention Analysis in the Walls of Fusion Devices — Application Notes
Laser-Induced Breakdown Spectroscopy (LIBS) is an innovative atomic emission spectroscopy technique that enables real-time, in-situ elemental analysis of surfaces in harsh environments, making it ide…
Quality First: A Guide to SEM-EDS Feature Analysis with Ultim Max and AZtecFeature — Webinars
Unlock the full potential of your SEM with a quality first approach to feature analysis. This tutorial demonstrates how Ultim Max EDS detectors and AZtecFeature software combin…
Using BEX and EDS to Perform Qualitative and Quantitative Analysis of Micro-Segregation in Steel — Application Notes
Segregation—the uneven distribution of alloying elements or impurities in steel—is an unavoidable thermodynamic process that occurs during casting. As the alloy cools, element migration c…
Advanced SEM–EDS-BEX and Automated Mineralogy for the Characterisation and Processing of Rare Earth Element Resources — Application Notes
Rare Earth Elements (REEs) are critical to the performance of modern technologies, underpinning sectors from renewable energy generation and electric transport, to high-performance consumer electroni…
Routine Moiré Imaging of Twisted 2D Materials — Application Video
Many AFM manufacturers show moiré images of twisted 2D materials, but it is not evident how long these images take to acquire.  Oxford Instrument's hi…
How low can you go? Investigating the importance of pattern resolution in EBSD — Application Notes
The collection of the diffraction pattern from the sample is a critical step in the Electron Backscatter Diffraction (EBSD) workflow, but equally important is the process by which that pattern is…
Time Domain NMR in R&D: studying the properties of plant-based meat analogue burgers during “cooking process” — Application Notes
Meat analogue products based on plant protein sources have been widely considered a rich replacement for conventional meat. The main reason for the increased interest in meat analogues is public awar…
How To Use IMARIS Latest AI Tools On Real Life Applications — Webinars
Learn how to streamline your image analysis by leveraging the latest AI segmentation tools in a user friendly and intuitive environment. Get more out of your image data than eve…
Diversification of Camera Technology in Support of Varied Wavefront Sensing Applications — Application Notes
Adoption of wavefront sensing instrumentation is increasing at optical and near-infrared ground-based observatories of all scales and configurations as a critical component of adaptive optics systems…
Diagnosing High-Energy-Density Plasmas Using Time-Gated Spectroscopy Of Thomson Scattered Light — Webinars
Thomson scattering is a powerful tool in the field of plasma physics, where scientists attempt to recreate the intense conditions found in extreme astrophysical environments and…
IR Driving Laser Beam Monitoring for HHG Sources — Solution Note
High Harmonic Generation (HHG) sources have been around since the late 1970’s, however, in recent times there has been significant steps in performance, smaller footprint and costs decrease tha…
High Speed X-Ray Beamline Imaging — Solution Note
Facilities such as synchrotrons and X-ray Free Electron Lasers (XFEL) have been the mainstay of UV and X-ray research for decades. The increasing popularity of affordable High Harmonic Generation (HH…
High Energy Photon Detection With First Light Imaging Cameras — Application Notes
Facilities such as synchrotrons and X-ray Free Electron Lasers (XFEL) have been the mainstay of UV and X-ray research for decades. Recent improvements to High Harmonic Generation (HHG) based sources …
Phase Transitions in Low Dimensional Materials Characterized by Raman Spectroscopy — Technical Article
We report how Raman spectroscopy is used to characterize a lithium intercalation induced phase transition in the Weyl semimetal WTe2. Low frequency Raman spectra, sensitive to inter-layer vibrational…
Uncovering Confocal Microscopy – Pairing Applications & Techniques — Webinars
Epifluorescence microscopes are extremely useful to visualise thin samples or tissue sections. Still, when samples are a bit thicker, the out of focus light will decrease signif…
Introducing MicroPoint 4 - A Powerful Tool for Photostimulation — Webinars
In this webinar, Dr Mark Browne, Microscopy Systems Director at Andor will introduce MicroPoint 4, with all-new smart controller, millisecond beam positioning and new solid stat…
What is Super Resolution Microscopy? Part 1 — Webinars
Super-resolution microscopy allows users to resolve fluorescently-labelled structures on size scales beyond the diffraction limit (200-300nm). In the past few years, super-resol…
Session 4 - Pushing the Limits – Optical Spectroscopy at the Extremes — Webinars
Having now covered the basics, we’ll look at several advanced applications that do the seemingly impossible, from counting individual photons to looking inside exploding p…
How to Cut and Split Imaris Surfaces — Tutorials
In this tutorial you will learn how to use the Cut Surface tool, which you can find inside the Surface Edit tab.  
Measuring Distances and Angles in Imaris — Tutorials
In this tutorial you will learn how to add Measurement Points to the Imaris scene. Using Measurement points you will be able to calculate distance between selected pairs of points or angles between l…
Session 3: Optimizing Equipment for Optical Spectroscopy — Webinars
After covering the “why”, we’ll now focus on the “how”. There are currently a dizzying array of tools available for spectroscopy, but the fundament…
iStar sCMOS Demo Video: How To Use Solis For Imaging Applications — Tutorials
Abstract The ns time scale measurement capability of the iStar intensified cameras allows for increasingly complex and novel measurements synchronized with a lab full of other …
Researchers Analyze 3D Pathology of Huntington’s Disease — Case Studies
Using Imaris image analysis software, Leslie Thompson and Isabella Inez Sanchez from the University of California-Irvine School of Medicine and colleagues discovered that Huntington’s disease s…
Monitoring Electronic Excitations in Oorganic Semiconductors with Ultrafast Optical Pump-probe Spectroscopy — Webinars
Polarization, time and energy-resolved optical pump-probe spectroscopy is a well-established tool to monitor charge-carrier dynamics on ultrafast timescales. The general idea is…
Micropoint Dye Laser System — Application Notes
MicroPoint provides a flexible and field-proven tool for photo-stimulation techniques such as bleaching, ablation and uncaging. The MicroPoint pulsed photo-stimulation system uses a Nitrogen (N2) pul…
Andor High Power Mosaic Lasers – SSL-HP Series — Application Notes
The Andor Mosaic® high performance laser diode modules (SSL-HP) have been created specifically to address the needs of high-end applications requiring superior optical quality, ultra-stable wavel…
Free Space Optical Communications and Adaptive Optics with C-RED 3 — Application Notes
C-RED 3 is a 640 x 512 SWIR camera running at 600 FPS full frame. It holds the legacy of all the developments of astronomical infrared fast wavefront sensors on top of specific features for industria…
High-speed Photometry with the Marana sCMOS Camera at the Planetary Transit Study Telescope — Application Notes
During the last decade, the successful operation of many ground-based (for example, CARMENES) and satellite (Kepler, TESS, eROSITA) surveys, usually for extrasolar planets, has led to an almost expon…
Automated classification of cavity coupled single photon emitters — Application Notes
The integration of quantum emitters, such as color centers in diamond, single molecules or colloidal quantum dots, with nano-photonic circuits enables quantum optic experiments on monolithic chips. I…
Spectrometer for Broadband Vibrational Sum-Frequency Generation at Fluid Interfaces — Application Notes
1. Principles of sum-frequency spectroscopy Broadband vibrational sum-frequency generation (SFG) is a second-order optical process that involves frequency mixing of three photons. Specifically, an b…
Quantitative Photoluminescence of Solar Cell Absorbers and the Quality of the Photo-Excited State — Application Notes
Research on novel thin film solar cells has always been motivated by the low material and energy consumption which is needed for the processing of this type of device. This approach appears promising…
Photoluminescence Mapping of GaN-Based Nanostructure Arrays — Application Notes
Since the beginning of the 1990s, the semiconductor GaN and its related compounds InN and AlN have taken a prominent position on the scene of semiconductor materials and devices. The successful p-typ…
Excition-Polariton Condensation Research using an Andor EMCCD — Case Studies
Research Group Dr Maciej Pieczarka is a postdoctoral fellow based in Assistant Professor Elena Ostrovskaya's group at the Nonlinear Physics Centre at the Australian National University. Dr Pieczarka…
Imaris 9.5 Launch Webinar – Tell your story even better with Imaris — Webinars
We know communicating the results from your imaging experiments is critically important for the success of your grants, publications and presentations. The 9.5 release of Imaris b…
Nobel Prize in Physics 2019 | Discoveries in Exoplanet Science — Application Notes
On 8th October 2019, James Peebles (Princeton University, USA), Michel Mayor and Didier Queloz (both from the University of Geneva, Switzerland) received the Nobel Prize “for contributions to o…
Endosome-Mitochondria Interactions Are Modulated by Iron Release from Transferrin — Webinars
  Margarida Barroso, Associate Professor at Albany Medical University discusses the transient “kiss and run" interactions between endosomes containing iron-bound-tra…
uDISCO for Whole Organs and Organisms - A New Method of Large Sample Imaging — Webinars
In this webinar Dr. Ali Ertürk, the inventor of 3DISCO, presents his outreaching uDISCO results as they have been published in Nature Methods. The provision of this paramount techn…
Detection of Nitrous Acid in the Jülich Atmosphere Simulation Chamber SAPHIR — Application Notes
The very reactive hydroxyl radicals (OH radicals) are the key species in almost all photochemical reactions which are responsible for the degradation and the removal of trace gases from the atmospher…
Passive and Whole Body CLARITY for Single Cell Phenotyping — Webinars
Speakers: Dr Benjamin E. Deverman, PhD (Senior Research Scientist, California Institute of Technology) and Arvonn Tully (Advanced Application Scientist, Bitplane) Understanding th…
Laser Induced Breakdown Spectroscopy of Copper Indium Gallium Selenide (CIGS) Thin Film Solar Cells — Application Notes
CIGS-based thin film solar modules are promising candidates for a cost-efficient conversion of solar energy into electricity. A thin film module consists of many single solar cells which are “m…