Imaris 11 – Automate the Routine, Amplify the Insight

Imaris 11 introduces Workflows, an intuitive step-by-step protocol system that streamlines 3D image analysis for researchers at all levels.

Simplify analysis protocols

Reproducible results

Save time using automation

Increase precision

Imaris: Accelerating Discovery Through Automated, Reproducible Analysis

Image analysis is often repetitive and time-consuming, with researchers manually performing identical steps across numerous datasets while struggling to share exact protocols for reproducibility.

Imaris 11 addresses these challenges by introducing Workflows that automate repetitive tasks through Batch processing and capture analysis steps in exportable protocols.

Researchers can now process large datasets efficiently, ensure reproducible results, and seamlessly share methods with collaborators - transforming image analysis from a bottleneck into an accelerator of discovery.

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Workflows - Batchable Image Analysis Protocols

With Imaris 11, you can effortlessly create a customized image analysis protocol (Workflow) tailored to your specific research area and requirements. These Workflows can be saved and applied to other datasets with just one click, streamlining your analysis process. Discover how Workflows can accelerate your journey from microscopy data to meaningful insights, impactful publications, and engaging conference presentations. Need assistance? Contact the Imaris Team to help you design the perfect Workflow for your research.

Microglial Synapse Engulfment

Imaris 11 simplifies microglial synapse engulfment analysis, transforming a complex, time-intensive process into a streamlined workflow. Surface segmentation detects microglia, while automated algorithms quantify engulfed synapses.

Workflows dramatically reduce analysis time while ensuring reproducibility and allowing researchers to compare synaptic engulfment between experimental groups with batch protocols.

Heart Vasculature Morphology

Analyzing heart vasculature is challenging: complex vessel networks require precise segmentation, manual tracing is time-consuming, and comparing cardiac compartments demands consistent methodology. Imaris 11 Workflows integrate machine learning pixel classification for automated vessel segmentation with Filament Tracer for precise quantification of vessel length and diameter, enabling reproducible analysis across multiple heart samples and compartments—transforming complex cardiac analysis into an efficient, shareable protocol.

Single-Cell Analysis of TFEB activation

Quantifying lysosomes and TFEB expression at the single-cell level traditionally requires multiple segmentation steps, making reproducibility challenging. Imaris 11 Workflows streamline this protocol by integrating Surface segmentation of cells and nuclei with Spot detection for lysosomes and TFEB into one automated, reproducible workflow. Statistics are compiled per cell while Batch Workflows enable consistent analysis and direct comparison across experimental groups through Vantage plotting tools.

Eleven New Functionalities in Imaris 11.0

Imaris 11.0 introduces a revolutionary approach to reproducible image analysis, designed to boost productivity and enhance results. Discover eleven powerful new features that elevate your analysis experience, streamline workflows, and deliver a transformative leap in data analysis. These innovations cover every essential step, including image preprocessing, quantification, visualization, batch processing, comparisons, and data plotting.

Workflow basics - Execute, Export, Import

Batch Workflow with Manual Steps

Analyse in Surface Regions of Interests (ROIs)

Batch importing Surfaces and Spots into Cell

Batch Snapshots and navigate between Views

1D & 2D Vantage for Comparative Analysis

Machine Learning Filtering of unwanted Spots

Extract Selected Statistics in one table

Batch Animations for Consistency

Mask or Delete Channels in a Batch mode

Two Options for Spine Diameter Calculations

Customer Publications

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Video Tutorials & Additional Resources

The Imaris Learning Center hosts a wide range of tutorial videos, how-to articles and webinars to guide you through the many features of Imaris. We have provided some links below which will get you started on some of our most recent developments.

Release Notes: Imaris 11.0
Discover Imaris 11 your way - self-study with expert-created workflows on sample images.

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Essential “How to” Video Tutorials to get started with Imaris 11.0

Dendritic Spine Segmentation

In this tutorial, learn three methods for dendritic spine segmentation in Imaris 11.0: manual drawing and editing, automatic detection in the Filament wizard, and automatic dete...

Set Up, Execute and Share a Workflow

In this tutorial, you will learn how to organize your image analysis into Workflows. These Workflows can be exported and reused to efficiently analyze other similar images with ...

Use and Adjust an existing Workflow

Workflows can be created and shared with your colleagues and other researchers. You can also request a Workflow setup from our Technical & Application Support Team. In this ...

Include a Manual Step in the Batch Analysis

Do you have an image analysis process that’s almost entirely automated, except for one step that must remain manual? Do you still want to run your analysis in Batch mode t...

Automate Your Analysis with Batch Mode and Compare Groups in Vantage

In this video, you’ll learn how to streamline your image analysis workflow by automating it with Workflows in Batch mode. Want to compare results across multiple experimen...

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